|
KMID : 1134820000290030531
|
|
Journal of the Korean Society of Food Science and Nutrition
2000 Volume.29 No. 3 p.531 ~ p.536
|
|
|
Effects of Water - Soluble Extract from Leaves of Morus alba and Cudrania tricuspidata on the Lipid Peroxidation in Tissues of Rats
|
|
Cha Jae-Young
Kim Hyun-Jung
Cho Young-Su
|
|
|
Abstract
|
|
|
|
The antioxidative activities of water-soluble extracts from leaves of Morus alba (MA) and Cudrania tricuspidata (CT) on the lipid peroxidation of rat tissues were studied in vivo system by measuring the formation of thiobarbituric acid reactive substances (TBARS). Male Sprague-Dawley rats received either a control diet (cholesterol diet) or cholesterol diets supplemented with 1% (w/w) MA or CT for 2 weeks. Body weight gain, food intakes, and relative weights of heart and spleen in rats were not significantly different among dietary groups. Relative weights of brain and liver in rats were higher in the MA diet than that in the CT and the control diets. The concentration of TBARS in kidney homogenates was significantly lower in the MA diet than that in the control diet, while this effect was not observed between the CT diet and the control diet. The concentrations of TBARS in brain and heart homogenates were significantly higher in the CT diet than those in the control and the MA diets. The concentrations of TBARS in liver microsomes induced with Fe^(2+)/ascorbate for 1 hr at 37℃ was effectively suppressed in the MA and CT diets compared with the control diet. These results suggest that the water-soluble extract from leaves of Morus alba inhibited lipid peroxidative formation in kidney and hepatic microsomes of cholesterol-fed rat.
|
|
|
KEYWORD
|
|
|
Morus alba, Cudrania tricuspidata, antioxidation, TBARS
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|